Bills vs. Colts final score prediction for NFL Week 10 (don’t count the Colts)

The Buffalo Bills and Indianapolis Colts will go down in an AFC battle in Week 10.

The Bills are firmly in first place in the AFC East at 7-2, good for second in the conference. They will face the Colts, who are currently the first team ranked No. 8. Indianapolis has a chance to return to the playoffs with a win on Sunday.

Let’s take a look at the latest odds for the game and then I’ll give my final score prediction.

Chance via FanDuel Sportsbook

Spread

Moneyline

Total

The Bills opened as 5-point favorites in this AFC game, but the line has since dropped half a point to Bills -4.5. The total for the game dropped by half a point from 47.0 to 46.5.

In this week’s edition of the “Road to 272 bets“, I wrote about why I’m taking the Colts to cover the spread as underdogs:

The Colts are a very different team with Joe Flacco at quarterback. Even after last week’s loss to the Vikings, they still looked like a more diverse offense with Flacco’s ability to throw the ball.

This week they host the Bills, who have had some issues playing on the road this season. The Bills have a Net Yards per Play of -0.7 away from home this season. Their average scoring margin also drops from +17.5 to +3.4.

If the Colts can run the ball successfully, which they should be able to do against a defense that allows 4.8 yards per carry, they can stay in this game and cover the spread as home underdogs.

When it comes to the total, I’ll take the UNDER. I expect both teams to largely stick to the run game, which keeps the clock running and limits explosive plays on the field. If Indianapolis sticks to that game plan, there’s a chance they can not only cover the spread, but win right away if they get upset.

Final score prediction: Bill 21, Colts 24

The odds are updated periodically and are subject to change.

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You can view them all Iain’s betting odds here!