4Monkeys escape from the Alpha Genesis lab in Yemassee, South Carolina

Police are warning residents in rural South Carolina to close their doors and windows after at least 43 monkeys escaped from a bioresearch lab.

The rhesus monkeys slipped out of an Alpha Genesis facility in Yemassee – just off I-95 in the southern part of the state – on Wednesday evening.

The company provides “primate research and development support to the scientific community,” according to its website.

None of the fugitive primates had been recaptured as of Thursday morning.

“We want to reassure the community that there are no health risks associated with these animals,” Yemassee police said.

Police and Alpha Genesis personnel have “strategically” set up traps in the area and are using thermal imaging cameras to track the monkeys.

Local residents have been warned “to keep doors and windows secured to prevent these animals from entering homes,” police said.

Residents are told not to approach the free-roaming monkeys, but instead to call 911 and report the sighting.

The Beaufort County Sheriff’s Office and state agriculture and wildlife officials are working with local law enforcement “to effectively and humanely manage this incident,” Yemassee police said.

It is unclear how the primates managed to break out.

Alpha Genesis Inc. did not immediately respond to The Post’s request for comment.

Rhesus macaques are native to India and China and are known for their high intelligence, according to National Geographic.

The apes have a long history of human medical and scientific research – and even preceded humans in going to space.

Yemassee is a small town of about 1,000 residents in Beaufort and Hampton counties in South Carolina’s Lowcountry, about 50 miles northwest of Savannah, Georgia.